I don't drink, but I do believe that wine has a medicinal purpose. Jesus turned water into wine and the bible says they saved the best for last. I believe the bible to be absolute truth, so I can't do away with this scripture just because I may think it's wrong to drink.
1 Timothy 5:23 Drink no longer water, but use a little wine for thy stomach's sake and thine often infirmities.
I do however know that the bible also teaches us to be not drunken.
Romans 13:13 Let us walk honestly, as in the day; not in rioting and drunkenness, not in chambering and wantonness, not in strife and envying.
People can pick one verse and make a sermon around it, but I believe God's word is all or nothing. You must take his whole word as truth and know that it will never contradict itself. If it teaches that wine is good for our infirmities, then it is good for our infirmities and if it tells us to be not drunken, then we should have enough common sense to know that to be drunken is not good for us in any way. I believe when it says "A little wine" that is what it means because anything more than a little would no longer be medicinal, but would make you drunken. You can not be drunken and still be in God’s will.